新一期JCO又出来了，继续和大家一起分享。

注重：已认领文章标题前加！！！

摘要链接： http://jco.ascopubs.org/content/vol26/issue10/

I期临床药理学试验

1.Phase I Pharmacokinetic and Pharmacodynamic Study of the Oral Mammalian Target of Rapamycin Inhibitor Everolimus in Patients With Advanced Solid Tumors
JCO Apr 1 2008: 1588–1595. First published on Mar 10 2008; 10.1200/JCO.2007.14.0988.

2.Dose- and Schedule-Dependent Inhibition of the Mammalian Target of Rapamycin Pathway With Everolimus: A Phase I Tumor Pharmacodynamic Study in Patients With Advanced Solid Tumors
JCO Apr 1 2008: 1603–1610. First published on Mar 10 2008; 10.1200/JCO.2007.14.5482.

支持治疗与生活质量

3.Randomized, Multicenter, Controlled Trial Comparing the Efficacy and Safety of Darbepoetin Alfa Administered Every 3 Weeks With or Without Intravenous Iron in Patients With Chemotherapy-Induced Anemia
JCO Apr 1 2008: 1611–1618.

4.Randomized Trial of Intravenous Iron Supplementation in Patients With Chemotherapy-Related Anemia Without Iron Deficiency Treated With Darbepoetin Alfa
JCO Apr 1 2008: 1619–1625.

胃肠道肿瘤

5.Wild-Type KRAS Is Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer
JCO Apr 1 2008: 1626–1634. First published on Mar 3 2008; 10.1200/JCO.2007.14.7116.

6.Complete Pathologic Response After Preoperative Chemotherapy for Colorectal Liver Metastases: Myth or Reality?
JCO Apr 1 2008: 1635–1641.

乳腺癌

7.Randomized Phase III Trial of Weekly Compared With Every-3-Weeks Paclitaxel for Metastatic Breast Cancer, With Trastuzumab for all HER-2 Overexpressors and Random Assignment to Trastuzumab or Not in HER-2 Nonoverexpressors: Final Results of Cancer and Leukemia Group B Protocol 9840
JCO Apr 1 2008: 1642–1649.

8.Phase III Randomized Placebo-Controlled Trial of Two Doses of Megestrol Acetate as Treatment for Menopausal Symptoms in Women With Breast Cancer: Southwest Oncology Group Study 9626
JCO Apr 1 2008: 1650–1656.

9.Clinical Classification of BRCA1 and BRCA2 DNA Sequence Variants: The Value of Cytokeratin Profiles and Evolutionary Analysis—A Report From the kConFab Investigators
JCO Apr 1 2008: 1657–1663.

10.Double-Blind, Randomized Placebo Controlled Trial of Fulvestrant Compared With Exemestane After Prior Nonsteroidal Aromatase Inhibitor Therapy in Postmenopausal Women With Hormone Receptor–Positive, Advanced Breast Cancer: Results From EFECT
JCO Apr 1 2008: 1664–1670. First published on Mar 3 2008; 10.1200/JCO.2007.13.5822.

11.Letrozole Suppresses Plasma Estradiol and Estrone Sulphate More Completely Than Anastrozole in Postmenopausal Women With Breast Cancer
JCO Apr 1 2008: 1671–1676.

12. Plasma Isoflavone Level and Subsequent Risk of Breast Cancer Among Japanese Women: A Nested Case-Control Study From the Japan Public Health Center-Based Prospective Study Group
JCO Apr 1 2008: 1677–1683. First published on Mar 3 2008; 10.1200/JCO.2007.13.9964.

13.Economic Evaluation Alongside a Clinical Trial of Psycho-Educational Interventions to Improve Adjustment to Survivorship Among Patients With Breast Cancer
JCO Apr 1 2008: 1684–1690.

14.Randomized Phase II Adjuvant Trial of Dose-Dense Docetaxel Before or After Doxorubicin Plus Cyclophosphamide in Axillary Node-Positive Breast Cancer

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